Chromatography
Chromatography is the science used in organic chemistry for separating and analyzing compounds, which studies the separation of molecules based on differences in their structure and/or composition. Chromatographic separations can be carried out using a variety of supports, including immobilized silica on glass plates (thin layer chromatography), volatile gases (gas chromatography), paper (paper chromatography), and liquids (liquid chromatography). Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a molecule. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measurement of their mass-to-charge ratios.
In analytical chemistry, sample preparation refers to the ways in which a sample is treated prior to its
analysis. Preparation is a very important step in most analytical techniques, because the techniques are
often not responsive to the analyte in its in-situ form, or the results are distorted by interfering species.
Sample preparation may involve dissolution, reaction with some chemical species, pulverizing, treatment
with a chelating agent (eg. EDTA), masking, Filtering, dilution, sub-sampling or many other techniques.
By some estimates, 60-80% of the work activity and operating cost in an analytical lab is spent
preparing samples for introduction into an analytical device.
Common methods for sample preparation include liquid-liquid extraction, centrifugation, and solid phase
extraction. Solid phase extraction (SPE) is one of the simplest, yet most effective and most versatile,
methods of sample preparation.
Chromatography product line features a range of instruments
Sample Preparation (Solid-phase extraction (SPE)) & Sample Introduction systems for ,GC, HPLC
GCMS & LCMS (MS) systems.
GC systems with special detectors like PFPD, ELSD, PID, NPD
O.I. Analytical– USA – Sample Introduction, Detection, Preparation & GC systems
